Current Publications in Pediatric Simulation

Newly Published Pediatric Simulation Articles for November 2021

  1. Alsem SC, van Dijk A, Verhulp EE, De Castro BO. Using virtual reality to treat aggressive behavior problems in children: A feasibility study. Clin Child Psychol Psychiatry [Internet]. 2021;26(4):1062–75. Available from: https://doi.org/10.1177/13591045211026160
  2. Bajwa NM, Nendaz MR, Posfay-Barbe KM, Yudkowsky R, Park YS. A Meaningful and Actionable Professionalism Assessment: Validity Evidence for the Professionalism Mini-Evaluation Exercise (P-MEX) Across 8 Years. Acad Med [Internet]. 2021;96(11S):S151–7. Available from: https://doi.rg/10.1097/ACM.0000000000004286
  3. Campbell-Yeo M, Dol J, Richardson B, McCulloch H, Hundert A, Foye S, et al. A co-design of clinical virtual care pathways to engage and support families requiring neonatal intensive care in response to the COVID-19 pandemic (COVES study). J Neonatal Nurs [Internet]. 2021;27(6):463–70. Available from: https://doi.org/10.1016/j.jnn.2021.06.010
  4. Charfeddine C, Laroussi N, Mkaouar R, Jouini R, Khayat O, Redissi A, et al. Expanding the clinical phenotype associated with NIPAL4 mutation: Study of a Tunisian consanguineous family with erythrokeratodermia variabilis-Like Autosomal Recessive Congenital Ichthyosis. PLoS One [Internet]. 2021;16(10):e0258777. Available from: https://doi.org/10.1371/journal.pone.0258777
  5. Comunale G, Padalino M, Maiorana C, Di Salvo G, Susin FM. Ventricular outflow tract obstruction: An in-silico model to relate the obstruction to hemodynamic quantities in cardiac paediatric patients. PLoS One [Internet]. 2021;16(10):e0258225. Available from: https://doi.rg/10.1371/journal.pone.0258225
  6. Cook TC, Camp-Spivey LJ. Innovative Teaching Strategies Using Simulation for Pediatric Nursing Clinical Education During the Pandemic: A Case Study. Acad Med [Internet]. 2021; Available from: https://doi.org/10.1097/ACM.0000000000004538
  7. Dao K, Fuchs A, André P, Giannoni E, Decosterd LA, Marchetti O, et al. Dosing strategies of imipenem in neonates based on pharmacometric modelling and simulation. J Antimicrob Chemother [Internet]. 2021 Nov 26;(dkab394). Available from: https://doi.org/10.1093/jac/dkab394
  8. Davis ML, Huang Y, Wang K. Rank normalization empowers a t-test for microbiome differential abundance analysis while controlling for false discoveries. Brief Bioinform [Internet]. 2021;22(5). Available from: https://doi.org/10.1093/bib/bbab059
  9. Degteva MO, Tolstykh EI, Shishkina EA, Sharagin PA, Zalyapin VI, Volchkova AY, et al. Stochastic parametric skeletal dosimetry model for humans: General approach and application to active marrow exposure from bone-seeking beta-particle emitters. PLoS One [Internet]. 2021;16(10):e0257605. Available from: https://doi.org/10.1371/journal.pone.0257605
  10. Dinur G, Borenstein-Levin L, Vider S, Hochwald O, Jubran H, Littner Y, et al. Evaluation of audio-voice guided application for neonatal resuscitation: a prospective, randomized, pilot study. J Perinat Med [Internet]. 2021;49(4):520–5. Available from: https://doi.org/10.1515/jpm-2020-0173
  11. Ebrahimpoor M, Goeman JJ. Inflated false discovery rate due to volcano plots: problem and solutions. Brief Bioinform [Internet]. 2021;22(5). Available from: http://doi.org/10.1093/bib/bbab053
  12. Gefen N, Rigbi A, Archambault PS, Weiss PL. Comparing children’s driving abilities in physical and virtual environments. Disabil Rehabil Assist Technol [Internet]. 2021;16(6):653–60. Available from: https://doi.org/10.1080/17483107.2019.1693644
  13. Haynes J, Bjorland P, Gomo Ø, Ushakova A, Rettedal S, Perlman J, et al. Novel Neonatal Simulator Provides High-Fidelity Ventilation Training Comparable to Real-Life Newborn Ventilation. Children [Internet]. 2021;8(10):1–12. Available from: https://doi.org/10.3390/children8100940
  14. He H, Cao X, Yin F, Wu T, Stauber T, Peng J. West Syndrome Caused By a Chloride/Proton Exchange-Uncoupling CLCN6 Mutation Related to Autophagic-Lysosomal Dysfunction. Mol Neurobiol [Internet]. 2021;58(6):2990–9. Available from: https://doi.org/10.1007/s12035-021-02291-3
  15. Herber S, Rodrigues FA, Vaccari A. Course for the qualification of nurses in the care of children with genetic diseases: an experience report. Rev Gauch Enferm [Internet]. 2021;42(spe):e20200193. Available from: https://doi.org/10.1590/1983-1447.2021.20200193
  16. Hinojosa PL, Eifinger F, Wagner M, Herrmann J, Wolf M, Ebenebe CU, et al. Anatomic accuracy, physiologic characteristics, and fidelity of very low birth weight infant airway simulators. Pediatr Res [Internet]. 2021;1–8. Available from: https://doi.org/10.1038/s41390-021-01823-w
  17. Hung C-H, Ho T-H, Lin C-Y. Investigating the Effectiveness of Using a Situated Simulation-Based Program to Improve Occupational Therapy Students’ Interactions and Observation Skills with Children. Occup Ther Int [Internet]. 2021;2021:1698683. Available from: https://doi.org/10.1155/2021/1698683
  18. Jacobson PA, Severin PN, Rumoro DP, Shah S. Mass-Casualty Training Exercise Using High-Fidelity Computerized Simulators and Involving Time and Resource Limitation. Prehosp Disaster Med [Internet]. 2021;36(3):313–20. Available from: https://doi.org/10.1017/S1049023X21000327
  19. Kainz H, Wesseling M, Jonkers I. Generic scaled versus subject-specific models for the calculation of musculoskeletal loading in cerebral palsy gait: Effect of personalized musculoskeletal geometry outweighs the effect of personalized neural control. Clin Biomech (Bristol, Avon) [Internet]. 2021;87:105402. Available from: https://doi.org/10.1016/j.clinbiomech.2021.105402
  20. Kalaniti K, Mugarab-Samedi V, Riehl A, Bingham W, Daspal S. Mission Possible: Keeping Families Connected During COVID-19 Pandemic. Oman Med J [Internet]. 2021;36(5):1–4. Available from: https://doi.org/10.5001/omj.2021.131
  21. Kristof Z, Eszlari N, Sutori S, Gal Z, Torok D, Baksa D, et al. P2RX7 gene variation mediates the effect of childhood adversity and recent stress on the severity of depressive symptoms. PLoS One [Internet]. 2021;16(6):e0252766. Available from: https://doi.org/10.1371/journal.pone.0252766
  22. Lee HN, Bae W, Park JW, Jung JY, Hwang S, Kim DK, et al. Virtual reality environment using a dome screen for procedural pain in young children during intravenous placement: A pilot randomized controlled trial. PLoS One [Internet]. 2021;16(8):e0256489. Available from: https://doi.org/10.1371/journal.pone.0256489
  23. McBryde ES, Meehan MT, Caldwell JM, Adekunle AI, Ogunlade ST, Kuddus MA, et al. Modelling direct and herd protection effects of vaccination against the SARS-CoV-2 Delta variant in Australia. Med J Aust [Internet]. 2021;215(9):427–32. Available from: https://doi.org/10.5694/mja2.51263
  24. Micallef J, Arutiunian A, Hiley J, Benson A, Dubrowski A. The Development of a Cost-Effective Infant Intraosseous Infusion Simulator for Neonatal Resuscitation Program Training. Cureus [Internet]. 2021;13(10):e18824. Available from: https://doi.org/10.7759/cureus.18824
  25. Miehlbradt J, Cuturi LF, Zanchi S, Gori M, Micera S. Immersive virtual reality interferes with default head-trunk coordination strategies in young children. Sci Rep [Internet]. 2021;11(1):17959. Available from: https://doi.org/10.1038/s41598-021-96866-8
  26. Philippon A-L, Truchot J, De Suremain N, Renaud M-C, Petit A, Baron G-L, et al. Medical students’ perception of simulation-based assessment in emergency and paediatric medicine: a focus group study. BMC Med Educ [Internet]. 2021;21(1):586. Available from: https://doi.org/10.1186/s12909-021-02957-5
  27. Poorbahrami K, Vignon-Clementel IE, Shadden SC, Oakes JM. A whole lung in silico model to estimate age dependent particle dosimetry. Sci Rep [Internet]. 2021;11(1):11180. Available from: https://doi.org/10.1038/s41598-021-90509-8
  28. Rajavi Z, Soltani A, Vakili A, Sabbaghi H, Behradfar N, Kheiri B, et al. Virtual Reality Game Playing in Amblyopia Therapy: A Randomized Clinical Trial. J Pediatr Ophthalmol Strabismus [Internet]. 2021;58(3):154–60. Available from: https://doi.org/10.3928/01913913-20210108-02
  29. Rana MJ, Goli S. The road from ICPD to SDGs: Health returns of reducing the unmet need for family planning in India. Midwifery [Internet]. 2021;103:103107. Available from: https://doi.org/10.1016/j.midw.2021.103107
  30. Saeedinia SA, Jahed-Motlagh MR, Tafakhori A, Kasabov N. Design of MRI structured spiking neural networks and learning algorithms for personalized modelling, analysis, and prediction of EEG signals. Sci Rep [Internet]. 2021;11(1):12064. Available from: https://doi.org/10.1038/s41598-021-90029-5
  31. Stamatas GN, Bensaci J, Greugny E, Kaur S, Wang H, Dizon MV, et al. A Predictive Self-Organizing Multicellular Computational Model of Infant Skin Permeability to Topically Applied Substances. J Invest Dermatol [Internet]. 2021;141(8):2049-2055.e1. Available from: https://doi.org/10.1016/j.jid.2021.02.012
  32. Uhrecký B, Gurňáková J, Marcinechová D. “We Ought to Be Professionals”: Strategies of Intrapersonal and Interpersonal Emotion Regulation of Emergency Medical Services Professionals in Confrontation With the Death of a Newborn in Simulated Task. Qual Health Res [Internet]. 2021;31(13):2364–77. Available from: https://doi.org/10.1177/10497323211037644
  33. Ustuner Top F, Kuzlu Ayyıldız T. Pain management in children during invasive procedures: A randomized clinical trial. Nurs Forum [Internet]. 2021;56(4):816–22. Available from: https://doi.org/10.1111/nuf.12616
  34. Verhoef REJ, van Dijk A, Verhulp EE, de Castro BO. Interactive virtual reality assessment of aggressive social information processing in boys with behaviour problems: A pilot study. Clin Psychol Psychother [Internet]. 2021;28(3):489–99. Available from: https://doi.org/10.1002/cpp.2620
  35. Wang F, Cai J, Wang J, He M, Mao J, Zhu K, et al. A novel WT1 gene mutation in a chinese girl with denys-drash syndrome. J Clin Lab Anal [Internet]. 2021;35(5):e23769. Available from: https://doi.org/10.1002/jcla.23769
  36. White P, Champion JD. Transitioning Undergraduate Maternal-Newborn and Pediatric Hospital Clinical Experience to Immersive Simulation-Based Education. Clin Simul Nurs [Internet]. 2021;61:10–3. Available from: https://doi.org/10.1016/j.ecns.2021.08.027
  37. Zhao Y, He H, Zang Y, Zhao L, Wang X. Population pharmacokinetics and dose simulation of cyclosporine in Chinese children with nephrotic syndrome: Effects of weight and total cholesterol. Int J Clin Pharmacol Ther [Internet]. 2021; Available from: https://doi.org/10.5414/CP203921
  38. Zheng Y, Wu S, Yang X. Analysis of Dix-Hallpike maneuver induced nystagmus based on virtual simulation. Acta Otolaryngol [Internet]. 2021;141(5):433–9. Available from: https://doi.org/10.1080/00016489.2021.1876247
  39. Zhu J, Zhao Y, Wang L, Zhou C, Zhou S, Chen T, et al. Physiologically based pharmacokinetic/pharmacodynamic modeling to evaluate the absorption of midazolam rectal gel. Eur J Pharm Sci [Internet]. 2021;167:106006. Available from: https://doi.org/10.1016/j.ejps.2021.106006









I am a UK-trained Neonatologist working in Starship NICU in Auckland, New Zealand. I am a member of the Douglas Starship Simulation faculty and lead the simulation programmer in NICU. My key simulation interests include education, communication and patient safety. I have been an active member of IPSS since 2011, member of the Education Committee since 2012, am a past Co-Chair of the Education Committee (2017-2018) and a current member of the Board of Directors. In collaboration with others, I established the IPSS-INSPIRE Fellowship in 2018 and am on the working group leading this initiative. My vision for IPSS is to continue to support collaborative knowledge sharing and research development in the pediatric and perinatal simulation community. My wish for IPSS is to see an increasing number of non-physician members and to support and develop the ability of those still at the early stage of simulation.



Dr. Carl Horsley

Intensivist, Counties Manukau Health, Auckland, New Zealand

Clinical Lead for Patient Safety, Health Quality and Safety Commission, New Zealand

Dr. Carl Horsley dual trained in Emergency Medicine and Intensive Care, and works clinically in the Critical Care Complex of Middlemore Hospital in Auckland, New Zealand. As part of his work there, he developed an in-situ simulation program specifically focused on building the adaptive capacity of the ICU team. This was put to the test in the Whakaari volcanic eruption with Middlemore being the national burns centre responding to a mass casualty event.

Carl is currently completing an MSc in Human Factors and System Safety at Lund University, Sweden with a thesis focusing on the sociology of safety.  He is also part of the Resilient Healthcare Society which is an international collaboration exploring the implications of resilience engineering in healthcare. As Clinical Lead for Patient Safety at the Health Quality Safety Commission, Carl is also involved in developing innovative approaches that support “work-as-done” by frontline to improve both patient care and staff wellbeing. He has published several book chapters on resilient healthcare and presented widely on the topic.


Dr. Andrew Petrosoniak

Emergency Physician & Trauma Team Leader, Assistant Professor

St. Michael’s Hospital and University of Toronto

Following an unsuccessful career as an intramural basketball player, Dr. Petrosoniak now works as an emergency physician and trauma team leader at St. Michael’s Hospital. He’s an assistant professor at the University of Toronto and an associate scientist at the Li Ka Shing Knowledge Institute. He’s the lead for translational simulation at St. Michael’s Hospital which involves the application of simulation techniques to identify issues and support the design of solutions related to healthcare delivery and improving health service outcomes.

More accurately, he seeks to reduce the number of F-bombs by providers linked to poor system/space design in healthcare. He also applies this work in the private sector as the co-founder of Advanced Performance Healthcare Design, a design and consulting firm that uses multi-modal simulation techniques to inform the design of clinical infrastructure, equipment and high performing teams.




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